CRISPR-CAS13A MEDIATED KNOCKDOWN OF ACRB MRNA EXPRESSION RESTORES CIPROFLOXACIN SUSCEPTIBILITY IN MULTIDRUG-RESISTANT KLEBSIELLA PNEUMONIAE

Authors

  • Raiha Ausaf Khan Kauser Abdulla Malik School of Life Sciences, Forman Christian College University Lahore Author
  • Zeeshan Ahmad Kauser Abdulla Malik School of Life Sciences, Forman Christian College University Lahore Author
  • Laiba Wadood Department of Pharmacy, The University of Lahore Author
  • Asim Patrick Department of Microbiology, Government College University Hyderabad, Sindh, Pakistan Author
  • Qandeel Abbas Soomro Department of Pathology, Indus Medical College, The University of Modern Science, Tando Muhammad Khan Sindh, Pakistan Author
  • Amna Noor Department of Pathology, Rawalpindi Medical University, Author
  • Raza Ullah Khan Centre for Omic Sciences, Islamia College Peshawar, KPK, Pakistan Author
  • Sheeza Riaz Department of Pharmacy, M. Islam college of pharmacy, Gujranwala Punjab Author
  • Urooj Fatima Department of Pharmacy, University of Lahore, Punjab Pakistan Author
  • Maaz Ahmad MBBS, NUMS (Army Medical College) Author

Keywords:

CRISPR-Cas13a, acrB Efflux Pump, Klebsiella pneumoniae, Ciprofloxacin Resistance, Multidrug Resistance, Transcriptional Knockdown, Antimicrobial Resistance.

Abstract

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Published

2026-08-31

Issue

Vol. 3 No. 02 (2026): Bioscience Insights

Section

Original Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

CRISPR-CAS13A MEDIATED KNOCKDOWN OF ACRB MRNA EXPRESSION RESTORES CIPROFLOXACIN SUSCEPTIBILITY IN MULTIDRUG-RESISTANT KLEBSIELLA PNEUMONIAE. (2026). Bioscience Insights, 3(02), 695-705. https://biosciinsights.com/index.php/BI/article/view/123