ILLNESS UNCERTAINTY AND JOB-RELATED AFFECTIVE WELL-BEING AMONG EMPLOYEES WITH URTICARIAL VASCULITIS RECRUITED FROM TERTIARY HOSPITALS IN PESHAWAR, PAKISTAN: THE MODERATING ROLE OF WORKPLACE ACCOMMODATION AVAILABILITY

Abstract

Urticarial vasculitis (UV) is a rare inflammatory condition characterized by recurrent wheals lasting more than 24 hours and histopathological evidence of small-vessel leukocytoclastic vasculitis. Its unpredictable course may affect attendance, concentration, commuting, task planning, disclosure and emotions at work. This worked analytical example demonstrates the planned analysis for a multicentre cross-sectional study examining illness uncertainty, workplace accommodation availability and job-related affective well-being among employed adults with specialist-documented UV. A computationally generated dataset of 186 records was used solely to illustrate statistical reporting; it contains no participant or hospital data. The proposed questionnaire combines the 23-item Mishel Uncertainty in Illness Scale–Community Form, the 20-item Job-related Affective Well-being Scale and Part 1 of the Workplace Accommodations, Benefits, Policies and Practices Scale. In a covariate-adjusted ordinary least-squares model using HC3 standard errors, illness uncertainty was negatively associated with job-related affective well-being at mean accommodation availability (b = −0.0189, SE = 0.0030, 95% CI [−0.0248, −0.0131], p < .001). Accommodation availability was positively associated with well-being at mean uncertainty (b = 0.0416, SE = 0.0124, 95% CI [0.0171, 0.0662], p < .001). The interaction was not statistically significant (b = 0.0007, SE = 0.0011, 95% CI [−0.0014, 0.0027], p = .541; ΔR² = .002). Accordingly, the worked analysis supports the two conditional main associations but not the hypothesized buffering effect.